Key result
Case report isolates novel adenovirus genotypes 31 and 49 from an AIDS patient with encephalitis.
Case Report (n=1)
This is the first report of isolating a mixture of adenoviruses (including the new candidate serotype 49) from a patient with adenovirus encephalitis.
May warrant adenovirus testing in AIDS encephalitis; leaves open the role of mixed new genotypes 31/49.
A mixture of adenoviruses 31 and 49 was isolated from the brain of an AIDS patient with encephalitis. Adenovirus hexon protein was detected in neurons by indirect immunofluorescence. By restriction endonuclease analysis both adenovirus 31 and 49 were shown to be new genotypes. This is the first report of the isolation of a mixture of adenoviruses from adenovirus encephalitis and the first association of adenovirus 49, a new candidate serotype, with encephalitis.
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Schnurr et al. (1995) conducted a case report in AIDS with encephalitis (n=1). Adenovirus 31 and 49 infection was evaluated on Isolation and identification of adenovirus genotypes. A mixture of adenoviruses 31 and 49, both new genotypes, was isolated from the brain of an AIDS patient with encephalitis.
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