Key result
Canine obesity is linked to higher serum triglycerides and altered lipoprotein profiles versus controls.
Why the study?
Does obesity alter serum lipid and lipoprotein concentrations in dogs?
Observational (n=26)
Does obesity alter serum lipid and lipoprotein concentrations in dogs?
Obese dogs exhibit abnormal lipoprotein profiles characterized by elevated triglycerides and altered phospholipid distribution, similar to patterns seen in human diabetes mellitus and canine acute pancreatitis.
Obesity alters canine lipid profiles; hypothesis-generating for metabolic parallels with humans but leaves open clinical translation.
Serum lipid and lipoprotein concentrations in 10 obese and 16 control dogs were examined. The serum triglyceride (TG) concentration in obese dogs was significantly higher than in control dogs. The serum concentrations of TG and phospholipid (PL) in beta lipoprotein and PL in pre-beta lipoprotein were significantly higher in obese dogs, while the serum PL concentration in alpha 1 lipoprotein was significantly lower in obese animals. In the serum total cholesterol concentration in obese dogs, a higher tendency for beta and pre-beta lipoproteins and lower tendency for alpha 1 lipoprotein were observed. These abnormal lipoprotein profiles were similar to those in diabetes mellitus in men and acute pancreatitis in dogs.
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Katamoto et al. (1995) conducted an observational in Obesity (n=26). Obesity vs. Control dogs was evaluated on Serum lipid and lipoprotein concentrations. Obese dogs exhibited significantly higher serum triglyceride concentrations and altered lipoprotein profiles compared to control dogs.
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