Key result
Immature platelet fraction may predict COVID-19 prognosis based on its septic and prothrombotic roles.
Why the study?
Platelet activation perpetuates ongoing systemic inflammation, and literature suggests a prognostic role for immature platelet fraction (IPF) in septic and prothrombotic settings, prompting review of its links with COVID-19.
The paper presents an elaborated account of the possible prognostic links between immature platelet fraction and COVID-19.
Supports further IPF investigation in COVID-19; should not yet change practice.
Prompted by the combination of an ever-evolving comprehension of the platelet activation as a pivotal perpetuator of an ongoing systemic inflammatory process and an encouraging literature on the prognostic role of immature platelet fraction (IPF) in septic and prothrombotic settings, we present an elaborated account of the possible prognostic links between IPF and Coronavirus disease 2019 (COVID-19).
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Jose et al. (2021) conducted a review in Coronavirus disease 2019 (COVID-19). Immature platelet fraction (IPF) was evaluated. Immature platelet fraction may have possible prognostic links with Coronavirus disease 2019 based on its role in septic and prothrombotic settings.
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