Key result
Cockcroft-Gault outperforms MDRD in predicting ICU stay and ventilation time after cardiac surgery.
Why the study?
Does the Cockcroft-Gault formula better predict short-term outcomes compared to the MDRD formula in patients undergoing cardiac surgery without renal failure?
Population
150 patients undergoing cardiac surgery and not affected by renal failure
Comparison
Preoperative glomerular filtration rate… vs Preoperative glomerular filtration rate…
Design
Cohort
Follow-up
until hospital discharge
Authors
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May favor Cockcroft-Gault over MDRD for postoperative risk prediction in cardiac surgery; hypothesis-generating and should not yet change practice.
Cohort (n=150)
Does the Cockcroft-Gault formula better predict short-term outcomes compared to the MDRD formula in patients undergoing cardiac surgery without renal failure?
The Cockcroft-Gault formula may be more powerful than the MDRD formula for predicting early postoperative clinical outcomes in cardiac surgery patients without baseline renal failure.
Luciani et al. (2010) conducted a cohort in Cardiac surgery (n=150). Cockcroft-Gault formula vs. MDRD formula was evaluated on Short-term outcomes including length of ICU stay, mechanical ventilation time, and length of in-hospital stay. The Cockcroft-Gault formula was a stronger predictor of ICU stay (P=0.002) and mechanical ventilation time (P<0.001) than the MDRD formula (P=0.007 and P=0.075) after cardiac surgery.
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