Key result
Nebulized magnesium sulphate reduces postoperative sore throat during swallowing at 4 hours vs normal saline.
Why the study?
Postoperative sore throat remains an unresolved complication after endotracheal intubation for general anaesthesia, prompting evaluation of magnesium sulphate nebulization to attenuate its incidence.
Does nebulized magnesium sulphate reduce the incidence of postoperative sore throat in patients undergoing endotracheal intubation for general anesthesia?
RCT (n=100)
No
Does nebulized magnesium sulphate reduce the incidence of postoperative sore throat in patients undergoing endotracheal intubation for general anesthesia?
p-value: p=<0.05
Nebulized magnesium sulphate is an effective and safe method to reduce the incidence of postoperative sore throat following endotracheal intubation.
Supports nebulized magnesium to mitigate early sore throat after intubation; confirms RCT efficacy and extends evidence for airway adjuncts.
Background: Postoperative sore throat (POST) is a well-recognized complication that remains unresolved in patients undergoing endotracheal intubation for general anaesthesia. The wide variation in these figures is presumably due to different skills and techniques among anesthetists and to differences between patients in the definition of sore throat. The main aim is to study the attenuating effect of Magnesium sulphate nebulization on the incidence of post-operative sore throat. Subjects and Methods: This is a prospective randomized clinical study. A total number of 100 patients of ASA grade 1 & 2, in the age group of 18 - 60 years. The study has been carried out at Sri Venkateswara Ram Narayana Ruia Government General Hospital, Sri Venkateswara Medical College, Tirupati, over a period of 12 months. Results: There was no significant difference among the groups in terms of age, gender and weight. Whereas Magnesium sulphate significantly lessens the POST during swallowing at 4th hour as compared to Normal saline (p< 0.05) and this statement can be attributed to any population. Conclusion: Post-operative sore throat is one of the most common undesirable anesthesia-associated problems in the patients undergoing GA with an endotracheal tube for routine surgical cases for up to 24 h. Magnesium sulphate was significantly reduces the incidence of POST compared to Normal saline , and it is safe, simple and effective in reducing postoperative sore throat.
No takes yet. Share an insight, caveat, or question.
Padma et al. (2020) conducted an RCT in Postoperative sore throat (n=100). Nebulized Magnesium sulphate vs. Normal saline was evaluated on Incidence of postoperative sore throat during swallowing at 4th hour (p=<0.05). Nebulized magnesium sulphate significantly reduced the incidence of postoperative sore throat during swallowing at the 4th hour compared to normal saline (p<0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: