Key result
Third-trimester pregnancy coincides with complete temporary remission of neurogenic orthostatic hypotension in one patient.
Case Report (n=1)
No
Pregnancy may temporarily alleviate symptoms of neurogenic orthostatic hypotension during the third trimester without altering underlying adrenergic function.
Single-case remission during pregnancy is hypothesis-generating; does not support practice change and requires confirmation.
A successful pregnancy and delivery in a patient with neurogenic orthostatic hypotension and a past medical history of achalasia is described. Surprisingly, she was free from orthostatic hypotension during the last trimester, though the evaluation of adrenergic function by measurements of changes in plasma norepinephrine on standing and by the response of blood pressure to infused norepinephrine revealed no difference between function before pregnancy and that during the last trimester. Orthostatic hypotension started again just after delivery.
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Sakoda et al. (1990) conducted a case report in Neurogenic orthostatic hypotension and achalasia (n=1). Pregnancy vs. Pre-pregnancy and post-delivery state was evaluated on Orthostatic hypotension symptoms and blood pressure response to standing. A patient with neurogenic orthostatic hypotension and achalasia experienced a complete, temporary remission of orthostatic hypotension during the last trimester of her pregnancy.
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