What is the clinical evidence from this study?

Study design: Observational. Population: Carotid artery stenosis (n=72). Intervention: Serum lipid indices (LDL-C/HDL-C, non-HDL-C/HDL-C, and TG/HDL-C ratios). Primary outcome: Development of carotid artery stenosis (p=0.119).

September 10, 2018The European Research JournalOpen Access

Effect of lipid parameters on carotid artery disease progression in patients undergoing carotid endarterectomy and unoperated patients with non-severe carotid artery stenosis

Q: What are the key findings of this study?

Serum lipid ratios, including LDL-C/HDL-C and non-HDL-C/HDL-C, were not independent predictors of the development of carotid artery stenosis (AUC 0.592 and 0.583, respectively).

Q: What does this research mean for the field?

Serum lipid ratios, including LDL-C/HDL-C, non-HDL-C/HDL-C, and TG/HDL-C, are not independent predictors of the development of carotid artery stenosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Serum lipid ratios fail to independently predict the development of carotid artery stenosis.

P=0.119
n=72

Why the study?

Are serum lipid ratios independent predictors of the development of severe carotid artery stenosis?

Population

72 patients, including 40 who underwent carotid endarterectomy and 32 unoperated patients with <50% carotid…

Design

Cohort

Authors

KÖKadir Kaan Özsin USUmut Serhat Sanrı FTFaruk Toktaş

Discussion

Member takes

Overview

Lipid indices may associate with CAS severity; leaves open whether they inform risk stratification or intervention thresholds.

Study Design

Type

Observational (n=72)

Structured PICO

Are serum lipid ratios independent predictors of the development of severe carotid artery stenosis?

Population

72 patients, comprising 40 who underwent carotid endarterectomy and 32 unoperated patients with <50% carotid artery stenosis, evaluated retrospectively.

Exposure

Serum lipid indices including LDL-C/HDL-C ratio, non-HDL-C/HDL-C ratio, and TG/HDL-C ratio

Outcome

Development of severe carotid artery stenosis (requiring CEA)surrogate

Main Result

p-value: p=0.119

Serum lipid ratios (LDL-C/HDL-C, non-HDL-C/HDL-C, TG/HDL-C) were not found to be independent predictors of the development of severe carotid artery stenosis requiring endarterectomy.

Cite This Study

Özsin et al. (2018) conducted an observational in Carotid artery stenosis (n=72). Serum lipid indices (LDL-C/HDL-C, non-HDL-C/HDL-C, and TG/HDL-C ratios) was evaluated on Development of carotid artery stenosis (p=0.119). Serum lipid ratios, including LDL-C/HDL-C and non-HDL-C/HDL-C, were not independent predictors of the development of carotid artery stenosis (AUC 0.592 and 0.583, respectively).

synapsesocial.com/papers/6aa682fb39a5015a928e5763 https://doi.org/10.18621/eurj.444384

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September 10, 2018The European Research JournalOpen Access

Effect of lipid parameters on carotid artery disease progression in patients undergoing carotid endarterectomy and unoperated patients with non-severe carotid artery stenosis

View Full Paper

Ask AI

Bookmark

Key result

Serum lipid ratios fail to independently predict the development of carotid artery stenosis.

P=0.119
n=72

Why the study?

Are serum lipid ratios independent predictors of the development of severe carotid artery stenosis?

Population

72 patients, including 40 who underwent carotid endarterectomy and 32 unoperated patients with <50% carotid…

Design

Cohort

Authors

KÖKadir Kaan Özsin USUmut Serhat Sanrı FTFaruk Toktaş

Discussion

Member takes

Overview

Lipid indices may associate with CAS severity; leaves open whether they inform risk stratification or intervention thresholds.

Study Design

Type

Observational (n=72)

Structured PICO

Are serum lipid ratios independent predictors of the development of severe carotid artery stenosis?

Population

72 patients, comprising 40 who underwent carotid endarterectomy and 32 unoperated patients with <50% carotid artery stenosis, evaluated retrospectively.

Exposure

Serum lipid indices including LDL-C/HDL-C ratio, non-HDL-C/HDL-C ratio, and TG/HDL-C ratio

Outcome

Development of severe carotid artery stenosis (requiring CEA)surrogate

Main Result

p-value: p=0.119

Serum lipid ratios (LDL-C/HDL-C, non-HDL-C/HDL-C, TG/HDL-C) were not found to be independent predictors of the development of severe carotid artery stenosis requiring endarterectomy.

Cite This Study

synapsesocial.com/papers/6aa682fb39a5015a928e5763 https://doi.org/10.18621/eurj.444384

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