June 25, 2020Damar Cerrahi DergisiOpen Access

The evaluation of predictive values of routine blood parameters for carotid artery disease in patients undergoing coronary artery bypass grafting

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Coronary artery disease requiring coronary artery bypass grafting (n=257). Intervention: Triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio vs. Lower TG/HDL-C ratio. Primary outcome: Concomitant significant carotid artery stenosis (≥50%) (OR 1.334, 95% CI 1.190-2.785, p=0.015).

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Key result

Higher preoperative TG/HDL-C ratio predicts ~33% higher odds of significant carotid stenosis in CABG patients.

OR 1.334
95% CI 1.190-2.785
P=0.015
n=257

Why the study?

To investigate the value of inflammatory biomarkers and atherogenicity index in predicting concomitant carotid artery stenosis in patients undergoing CABG.

Do routine blood parameters like TG/HDL-C ratio predict concomitant significant carotid artery stenosis in patients undergoing CABG?

Population

257 patients scheduled for isolated CABG

Comparison

Significant CAS (≥50%) vs without significant CAS

Design

Retrospective study

Authors

MTMehmet Tercan

Discussion

Member takes

Overview

The TG/HDL-C ratio, a routine blood parameter, may serve as a useful independent predictor for concomitant significant carotid artery stenosis in patients undergoing CABG.

Study Design

Type

Observational (n=257)

Multicenter

Structured PICO

Do routine blood parameters like TG/HDL-C ratio predict concomitant significant carotid artery stenosis in patients undergoing CABG?

Population

257 patients (mean age 59.2 years, 36.6% female) scheduled for isolated coronary artery bypass grafting, evaluated retrospectively for predictors of concomitant significant carotid artery stenosis.

Exposure

Routine blood parameters including triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, mean platelet volume, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio

Outcome

Presence of concomitant significant carotid artery stenosis (CAS ≥50%)surrogate

Main Result

Odds Ratio: 1.334 (95% CI 1.19–2.785)

p-value: p=0.015

The TG/HDL-C ratio, a routine blood parameter, may serve as a useful independent predictor for concomitant significant carotid artery stenosis in patients undergoing CABG.

Limitations

Single-center design
Retrospective design
Small sample size
Use of Doppler ultrasound, which is an operator-dependent tool

Cite This Study

Mehmet Tercan (2020) conducted an observational in Coronary artery disease requiring coronary artery bypass grafting (n=257). Triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio vs. Lower TG/HDL-C ratio was evaluated on Concomitant significant carotid artery stenosis (≥50%) (OR 1.334, 95% CI 1.190-2.785, p=0.015). A higher preoperative triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio independently predicted concomitant significant carotid artery stenosis in patients undergoing CABG (OR 1.334).

synapsesocial.com/papers/6aa2e71e3c35dfb37e2078de https://doi.org/10.9739/tjvs.2020.729

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June 25, 2020Damar Cerrahi DergisiOpen Access

The evaluation of predictive values of routine blood parameters for carotid artery disease in patients undergoing coronary artery bypass grafting

View Full Paper

Ask AI

Bookmark

Key result

Higher preoperative TG/HDL-C ratio predicts ~33% higher odds of significant carotid stenosis in CABG patients.

OR 1.334
95% CI 1.190-2.785
P=0.015
n=257

Why the study?

To investigate the value of inflammatory biomarkers and atherogenicity index in predicting concomitant carotid artery stenosis in patients undergoing CABG.

Do routine blood parameters like TG/HDL-C ratio predict concomitant significant carotid artery stenosis in patients undergoing CABG?

Population

257 patients scheduled for isolated CABG

Comparison

Significant CAS (≥50%) vs without significant CAS

Design

Retrospective study

Authors

MTMehmet Tercan

Discussion

Member takes

Overview

The TG/HDL-C ratio, a routine blood parameter, may serve as a useful independent predictor for concomitant significant carotid artery stenosis in patients undergoing CABG.

Study Design

Type

Observational (n=257)

Multicenter

Structured PICO

Do routine blood parameters like TG/HDL-C ratio predict concomitant significant carotid artery stenosis in patients undergoing CABG?

Population

257 patients (mean age 59.2 years, 36.6% female) scheduled for isolated coronary artery bypass grafting, evaluated retrospectively for predictors of concomitant significant carotid artery stenosis.

Exposure

Routine blood parameters including triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, mean platelet volume, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio

Outcome

Presence of concomitant significant carotid artery stenosis (CAS ≥50%)surrogate

Main Result

Odds Ratio: 1.334 (95% CI 1.19–2.785)

p-value: p=0.015

The TG/HDL-C ratio, a routine blood parameter, may serve as a useful independent predictor for concomitant significant carotid artery stenosis in patients undergoing CABG.

Limitations

Single-center design
Retrospective design
Small sample size
Use of Doppler ultrasound, which is an operator-dependent tool

Cite This Study

synapsesocial.com/papers/6aa2e71e3c35dfb37e2078de https://doi.org/10.9739/tjvs.2020.729

Also Consider

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