Key result
Look-Locker T1 mapping strongly correlates with post-contrast MOLLI for highly reproducible ECV quantification.
Why the study?
Are Look-Locker and MOLLI T1 mapping techniques reproducible for quantifying myocardial extracellular volume in patients with cardiomyopathy?
Population
10 patients with the diagnosis of cardiomyopathy (5 with delayed contrast enhancement and 5 without)
Design
Cross-sectional, 3 investigators blinded to clinical data
Authors
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Both techniques support reproducible ECV research use in cardiomyopathy; leaves open impact on clinical decisions.
Observational (n=10)
Single-blind
No
Are Look-Locker and MOLLI T1 mapping techniques reproducible for quantifying myocardial extracellular volume in patients with cardiomyopathy?
Effect estimate: R2 0.82
p-value: p=< 0.001
Look-Locker and MOLLI T1 mapping techniques demonstrate high interobserver and intraobserver reproducibility for evaluating myocardial extracellular volume.
Yingchoncharoen et al. (2014) conducted an observational in Cardiomyopathy (n=10). T1 mapping techniques (Look-Locker, MOLLI_Pre, MOLLI_Post) was evaluated on Correlation between Look-Locker T1 and Post-contrast MOLLI (R2 0.82, p=< 0.001). Look-Locker T1 mapping was strongly correlated with post-contrast MOLLI (R2 0.82, p < 0.001), and both techniques demonstrated high reproducibility for extracellular volume quantification.
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