Key result
ShMOLLI and MOLLI T1 mapping techniques yielded equivalent extracellular volume measurements (0.29 vs 0.30) in hypertrophic cardiomyopathy despite a significant 47 ms bias in absolute T1 values.
Why the study?
Do ShMOLLI and 5(4R)3 MOLLI T1 mapping sequences yield similar ECV measurements in patients with HCM?
Population
11 patients with hypertrophic cardiomyopathy (HCM) undergoing CMR
Comparison
5(4R)3 variant of MOLLI T1 mapping sequence vs ShMOLLI T1 mapping sequence
Design
Cross-sectional
Authors
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Supports interchangeable ECV assessment by ShMOLLI or MOLLI in HCM; leaves open effects of T1 bias on other applications.
Cross-Sectional (n=11)
No
Do ShMOLLI and 5(4R)3 MOLLI T1 mapping sequences yield similar ECV measurements in patients with HCM?
Absolute Event Rate: 0.29% vs 0.3%
p-value: p=0.08
ShMOLLI and MOLLI T1 mapping sequences yield similar ECV measurements in HCM patients despite significant differences in absolute T1 values.
González et al. (2015) conducted a cross-sectional in Hypertrophic cardiomyopathy (HCM) (n=11). ShMOLLI T1 mapping vs. 5(4R)3 MOLLI T1 mapping was evaluated on Extracellular volume (ECV) (p=0.08). ShMOLLI and MOLLI T1 mapping techniques yielded equivalent extracellular volume measurements (0.29 vs 0.30) in hypertrophic cardiomyopathy despite a significant 47 ms bias in absolute T1 values.
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