What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Healthy aging (n=152). Intervention: Aging vs. Younger age groups. Primary outcome: Ventricular volume index and free space volume index.

What does this research mean for the field?

Age-related increases in ventricular volume begin in the forties for men and fifties for women, whereas expansion of subarachnoid free spaces (cisternae and sulci) does not increase until the sixties. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Quantify age-related enlargement of supratentorial ventricles and subarachnoid spaces (cisternae and sulci) in neurologically healthy individuals across adulthood.

April 1, 1985Journal of the American Geriatrics Society

Age‐related Change in Volumes of the Ventricles, Cisternae, and Sulci: A Quantitative Study Using Computed Tomography

View Full Paper

Ask AI

Bookmark

Key result

Age-related ventricular enlargement begins earlier in men than women and precedes free space expansion.

n=152

Population

152 individuals (97 men, 55 women) with no neurologic disturbances, aged 17 to 86 years.

Design

Cross-sectional

Authors

STShumpei TakedaTohoku University TMT MatsuzawaMirai Hospital

Discussion

Member takes

Implication

Sex-specific ventricular enlargement patterns warrant caution in geriatric neuroimaging interpretation; leaves open links to hypertension and longitudinal outcomes.

Key Points

Quantify age-related enlargement of supratentorial ventricles and subarachnoid spaces (cisternae and sulci) in neurologically healthy individuals across adulthood.
Analyzed cranial computed tomography scans of 152 neurologically normal participants (97 men and 55 women) aged 17 to 86 years.
Calculated supratentorial ventricular volume index and free space volume index normalized to total cranial cavity volume.
Ventricular volume and ventricular volume index increased significantly starting in the forties in men and in the fifties in women.
Free space volume and free space volume index showed significant enlargement only after the sixties in both sexes.
Hypertensive men older than 65 years exhibited smaller ventricular and free space volume indexes than normotensive peers.

Study Design

Type

Cross-Sectional (n=152)

Structured PICO

Population

152 adults aged 17 to 86 years with no neurologic disturbances evaluated for age-related changes in ventricular and free space volumes using computed tomography.

Outcome

Ventricular volume index and free space volume indexsurrogate

Brain ventricular and free space volumes increase with age, with ventricular enlargement beginning earlier in men than women, and these volumes are smaller in older hypertensive men.

Cite This Study

Takeda et al. (1985) conducted a cross-sectional in Healthy aging (n=152). Aging vs. Younger age groups was evaluated on Ventricular volume index and free space volume index. Age-related increases in ventricular volume began in the 40s for men and 50s for women, whereas free space volume increased in the 60s for both sexes.

synapsesocial.com/papers/6aa69cca7b142bbe3664d59e https://doi.org/10.1111/j.1532-5415.1985.tb07114.x

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

Sex-specific ventricular enlargement patterns warrant caution in geriatric neuroimaging interpretation; leaves open links to hypertension and longitudinal outcomes.

Age‐related Change in Volumes of the Ventricles, Cisternae, and Sulci: A Quantitative Study Using Computed Tomography

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Age‐related Change in Volumes of the Ventricles, Cisternae, and Sulci: A Quantitative Study Using Computed Tomography

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider