Key result
CRBBB and LAH in postoperative ToF are linked to ~40% mortality alongside impaired LV function.
Why the study?
What are the long-term clinical and hemodynamic outcomes in patients who survived corrective surgery for tetralogy of Fallot?
Cohort (n=84)
What are the long-term clinical and hemodynamic outcomes in patients who survived corrective surgery for tetralogy of Fallot?
Patients who survive corrective surgery for tetralogy of Fallot have a 4% incidence of sudden death over 5 years (highest with CRBBB and LAH) and exhibit impaired left ventricular function.
Elevated sudden death risk after tetralogy of Fallot repair with CRBBB, LAH, and LV impairment may warrant closer surveillance; leaves open optimal risk stratification and interventions.
(1) The ECGs of 84 patients who survived corrective surgery for tetralogy of Fallot were reviewed. The overall incidence of sudden death during at least 5 years period of follow-up was 4%, mortality being highest in those with CRBBB and LAH (40%). (2) The ratio of leftward to rightward QRS forces projected on the X axis (Rs/Sx) is significantly decreased in postoperative T/F patients. (3) Twenty-seven patients who had corrective surgery for tetralogy of Fallot underwent cardiac catheterization postoperatively. LVEF was mildly, but significantly diminished and LVEDV was increased significantly, while peak dp/dt, Vpm and Vmax were significantly depressed. These findings indicate that patients who had corrective surgery for tetralogy of Fallot have impaired left ventricular function.
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Nishioka et al. (1980) conducted a cohort in Tetralogy of Fallot (n=84). Corrective surgery for tetralogy of Fallot was evaluated on Sudden death. Postoperative tetralogy of Fallot patients had a 4% incidence of sudden death over at least 5 years, with mortality reaching 40% in those with CRBBB and LAH, alongside impaired left ventricular function.
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