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April 1, 1978CirculationOpen Access

Left ventricular function following attempted surgical repair of tetralogy of Fallot.

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Why the study?

Does a satisfactory hemodynamic repair of tetralogy of Fallot result in better long-term left ventricular function compared to an unsatisfactory repair?

Population

40 patients (ages 3-27), 1-12 years following attempted surgical repair of tetralogy of Fallot.

Comparison

Satisfactory surgical repair of tetralogy of… vs Unsatisfactory surgical repair of tetralogy of…

Design

Cohort

Follow-up

1-12 years

Authors

ARAlbert P. RocchiniJKJohn F. KeaneMFMichael D. Freed

Discussion

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Overview

Satisfactory TOF repair was associated with preserved LV function; leaves open whether hemodynamic optimization improves outcomes in prospective studies.

Structured PICO

Does a satisfactory hemodynamic repair of tetralogy of Fallot result in better long-term left ventricular function compared to an unsatisfactory repair?

P
Population
40 patients (ages 3-27), 1-12 years following attempted surgical repair of tetralogy of Fallot.
I
Intervention
Satisfactory surgical repair of tetralogy of Fallot (Qp/Qs ≤ 1.5 and right ventricular systolic pressure ≤ 60% of left ventricular value)
C
Comparator
Unsatisfactory surgical repair of tetralogy of Fallot (Qp/Qs > 1.5 and/or right ventricular systolic pressure > 60% of left ventricular value)
O
Outcome
Left ventricular function (left ventricular end-diastolic volume, end-diastolic pressure, ejection fraction, and mass) assessed by angiographic methodssurrogate

Patients with satisfactory hemodynamic repair of tetralogy of Fallot maintain normal left ventricular function, whereas those with unsatisfactory hemodynamics show significant left ventricular impairment.

Cite This Study

Rocchini et al. (1978) studied this question.

synapsesocial.com/papers/6a716fe1fe4101aa97e09271https://doi.org/10.1161/01.cir.57.4.798
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Right ventricular volume characteristics before and after palliative and reparative operation in tetralogy of Fallot.1976 · 105 citations
  2. 2Early and Late Results After Intracardiac Repair of Tetralogy of Fallot1965 · 138 citations
  3. 3Total correction of tetralogy of Fallot. Review of ten years' experience.1968 · 27 citations