August 1, 1972Circulation
Phenomenon of Supernormality in the Human Heart
Key result
Electrophysiologic mechanisms likely explain supernormal cardiac conductivity and excitability over hemodynamic or vagal theories.
- n=8
Why the study?
What is the electrophysiologic mechanism of supernormality in the human heart?
Population
8 patients
Design
Case_series
Authors
Discussion
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Member takes
Implication
Case report supports electrophysiologic mechanisms; leaves open prospective validation before any clinical adoption.
Study Design
Type
Case Report (n=8)
Structured PICO
What is the electrophysiologic mechanism of supernormality in the human heart?
P
Population
8 patients with supernormal conductivity (5 cases) or excitability (3 cases) evaluated via electrocardiograms and His bundle electrograms.
E
Exposure
Electrophysiologic evaluation including atropine administration and electrically induced premature atrial beats
O
Outcome
Mechanism and location of supernormal conductivity and excitability via electrocardiograms and His bundle electrogramssurrogate
The phenomenon of supernormality in the human heart is likely driven by electrophysiologic mechanisms in the bundle branches rather than vagal or hemodynamic factors.
Cite This Study
Massumi et al. (1972) conducted a case report in Supernormal conductivity and excitability (n=8). Supernormal conductivity and excitability was evaluated on Mechanism of supernormality. Supernormal conductivity and excitability in the human heart are likely explained by electrophysiologic mechanisms rather than hemodynamic or vagal theories.