Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions

A highly efficient and simple synthesis of dithiocarbamates is reported in the one-pot reaction of amines, CS 2 , and alkyl halides without using a catalyst under solvent-free conditions.The mild reaction conditions, high yields, and broad scope of the reaction illustrate the good synthetic utility of this method.The reaction is a highly atom-economic process for production of dithiocarbamates and can be successfully used in large amount for the pharmaceutical or agrochemical industries.