Key result
Elevated NLR and RDW predict higher 2-year CV mortality in STEMI after emergency PCI.
Why the study?
Existing clinical risk scores for death in acute STEMI are complex to calculate and unsuitable for primary hospitals, whereas NLR and RDW are routine, easily obtainable blood markers.
Do neutrophil to lymphocyte ratio and red cell distribution width predict cardiovascular death in patients with STEMI after emergency PCI?
Observational (n=181)
No
Do neutrophil to lymphocyte ratio and red cell distribution width predict cardiovascular death in patients with STEMI after emergency PCI?
Odds Ratio: 1.122 (95% CI 1.041–1.21)
p-value: p=0.003
NLR and RDW are easily obtainable routine blood indicators that independently predict long-term cardiovascular death in STEMI patients following emergency PCI.
May support simple NLR/RDW risk stratification in primary-hospital STEMI care; leaves open prospective validation against established scores.
There are many clinical scoring criteria for predicting the risk of death in patients with acute ST-segment elevation myocardial infarction (STEMI), but most of the indicators are complex to calculate and are not suitable for use in primary hospitals. Neutrophil to lymphocyte ratio (NLR) and red cell distribution width (RDW) are blood routine indicators that are easy to obtain and may help primary hospitals to evaluate the risk of death in patients with STEMI. Our aim was to explore the predictive value of NLR combined with RDW in the long-term prognosis of patients with STEMI after emergency percutaneous coronary intervention (PCI). A total of 181 patients with STEMI who underwent emergency PCI in the Affiliated Hospital of Pu-tian University from January 2017 to August 2018 were selected. Clinical profile, prognosis of all patients were collected. P value < 0.05 was considered significant. In all patients, cardiovascular death during the follow-up period was defined as cardiovascular death group, and surviving during the follow-up period was defined as survival group. There were no significant differences in demography and comorbidities between the two groups. The differences between the two groups in NLR, RDW, C-reactive protein, N-terminal-pro B type natriuretic peptide were statistically significant (P < 0.01). Binary logistic regression analysis showed that NLR (OR = 1.122, 95% CI 1.041 ~ 1.210, P = 0.003) and RDW (OR = 1.288, 95% CI 1.126 ~ 1.472, P = 0.0005) were important predictors of mortality in patients with STEMI (P < 0.05). Kaplan-Meier analysis showed that as the NLR increased, the risk of death increased (P < 0.001). In conclusion, NLR and RDW are independent predictors of cardiovascular death in patients with STEMI, and they have a certain predictive value.
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Lin et al. (2021) conducted an observational in ST segment elevation myocardial infarction (STEMI) (n=181). Neutrophil to lymphocyte ratio (NLR) and red cell distribution width (RDW) vs. Lower levels of NLR and RDW was evaluated on Cardiovascular death (OR 1.122, 95% CI 1.041-1.210, p=0.003). Elevated neutrophil to lymphocyte ratio (OR 1.122) and red cell distribution width (OR 1.288) are independent predictors of 2-year cardiovascular mortality in patients with STEMI after emergency PCI.
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