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January 1, 2008Annals of Vascular DiseasesOpen Access

Soleal vein thrombosis affects ~98% of legs with DVT in fatal pulmonary embolism.

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Population

60 autopsy cases (120 legs) with fatal pulmonary thromboembolism

Design

Case_series

Key result

In 60 autopsy cases with fatal pulmonary thromboembolism, the soleal vein was the most frequent site of deep vein thrombosis, present in 115 of the 117 legs with detected thrombi.

Authors

NKNorimasa KageyamaARAyako RoTTTakanobu Tanifuji

Discussion

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Overview

Soleal vein focus in fatal PE warrants further study; hypothesis-generating and should not yet change prophylaxis practice.

Study Design

Type

Observational (n=60)

Structured PICO

P
Population
60 autopsy cases (120 legs) with fatal pulmonary thromboembolism examined to determine the anatomical distribution of deep vein thrombosis.
O
Outcome
Frequency and location of deep vein thrombosis (fresh and organized thrombi)surrogate

The soleal vein is the primary site of deep vein thrombosis formation in patients with fatal pulmonary thromboembolism, highlighting its importance for VTE prophylaxis.

Limitations

  • Lack of clinical verification of crural vein thrombosis by diagnostic imaging such as ultrasonography or MRI prior to autopsy

Cite This Study

Kageyama et al. (2008) conducted an observational in Fatal pulmonary thromboembolism (n=60). Anatomical characteristics of crural veins was evaluated on Frequency of soleal vein thrombosis among legs with deep vein thrombosis. In 60 autopsy cases with fatal pulmonary thromboembolism, the soleal vein was the most frequent site of deep vein thrombosis, present in 115 of the 117 legs with detected thrombi.

synapsesocial.com/papers/6aa6c61446e2dc21629222d7https://doi.org/10.3400/avd.avdoa07004
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Significance of the Soleal Vein and Related Drainage Veins, in Calf Vein Thrombosis in Autopsy Cases with Massive Pulmonary Thromboembolism2015 · 40 citations
  2. 2Pulmonary Embolism in Patients with Isolated Soleal Vein Thrombosis1998 · 120 citations
  3. 3The origin of deep vein thrombosis: a venographic study1971 · 306 citations
  4. 4Pathophysiology of Venous Thromboembolism with Respect to the Anatomical Features of the Deep Veins of Lower Limbs: A Review2017 · 37 citations
  5. 5The origin of thrombi in the deep veins of the lower limb: A venographic study1978 · 60 citations