Population
100 autopsy cases of lethal pulmonary thromboembolism (PE) resulting from limb deep vein thrombosis (DVT)
Design
Case_series
Key result
In 100 autopsy cases of fatal massive pulmonary thromboembolism, calf veins were involved in 100% of limbs with deep vein thrombosis, with isolated calf DVTs present in 47% of patients.
Authors
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Soleal vein thrombi predominate as DVT origin in fatal PE autopsies; hypothesis-generating for targeted surveillance in immobilized patients.
Observational (n=100)
No
The soleal vein appears to be the primary site of DVT initiation, which then propagates proximally to cause lethal pulmonary thromboembolism.
Ro et al. (2015) conducted an observational in Massive pulmonary thromboembolism (n=100). Calf vein and soleal vein involvement vs. Other deep venous segments was evaluated on Distribution and chronology of deep vein thrombosis in each deep venous segment. In 100 autopsy cases of fatal massive pulmonary thromboembolism, calf veins were involved in 100% of limbs with deep vein thrombosis, with isolated calf DVTs present in 47% of patients.