Key result
In patients with annuloaortic ectasia, the David I procedure and modified Bentall procedure showed excellent results, with early mortality of 2.5% and 3.0%, respectively.
Why the study?
Does the David I procedure improve long-term outcomes compared to the modified Bentall procedure in patients with annuloaortic ectasia?
Cohort (n=181)
Does the David I procedure improve long-term outcomes compared to the modified Bentall procedure in patients with annuloaortic ectasia?
Absolute Event Rate: 2.5% vs 3%
Both the modified Bentall and David I procedures show excellent early and late results for annuloaortic ectasia, though they present different long-term complication profiles.
Both techniques show low early mortality and good late survival; leaves open superiority of David I over modified Bentall in annuloaortic ectasia.
BACKGROUND: Patients with annuloaortic ectasia may be surgically treated with modified Bentall or David I valve-sparing procedures. Here, we compared the long-term results of these procedures. METHODS: A total of 181 patients with annuloaortic ectasia underwent modified Bentall (102 patients, Group 1) or David I (79 patients, Group 2) procedures from 1994 to 2015. Mean age was 62 ± 11 years in Group 1 and 64 ± 16 years in Group 2. Group 1 patients were in poorer health, with a lower ejection fraction and higher functional class. RESULTS: Early mortality was 3% in Group 1 and 2.5% in Group 2. Patients undergoing a modified Bentall procedure had a higher incidence of thromboembolism and hemorrhage, whereas those undergoing a David I procedure had a higher incidence of endocarditis. Actuarial survival was 70 ± 6% at 15 years in Group 1 and 84 ± 7% at 10 years in Group 2. Actuarial freedom from reoperation was 97 ± 2% at 15 years in Group 1 and 84 ± 7% at 10 years in Group 2. In Group 2, freedom from procedure-related reoperations was 98 ± 2% at 10 years. At last follow-up, no cases of moderate or severe aortic regurgitation were observed. CONCLUSIONS: The modified Bentall and David I procedures showed excellent early and late results. The modified Bentall procedure with a mechanical conduit was associated with thromboembolic and hemorrhagic complications, whereas the David I procedure was associated with unexplained occurrences of endocarditis. Thus, the David I procedure appears to be safe, reproducible, and capable of achieving stable aortic valve repair and is therefore our currently preferred solution for patients with annuloaortic ectasia. However, the much shorter follow-up for David I patients limits the strength of our comparison between the two techniques.
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Martino et al. (2017) conducted a cohort in Annuloaortic ectasia (n=181). David I procedure vs. Modified Bentall procedure was evaluated on Early mortality. In patients with annuloaortic ectasia, the David I procedure and modified Bentall procedure showed excellent results, with early mortality of 2.5% and 3.0%, respectively.
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