Key result
Necropsy of a patient with apical hypertrophic cardiomyopathy revealed extensive myocardial disarray and fibrosis near the apex, suggesting it is a variant of classic hypertrophic cardiomyopathy.
Case Report (n=1)
No
Necropsy findings of a patient with apical hypertrophic cardiomyopathy showed extensive myocardial disarray near the apex, suggesting it is a variant of classic hypertrophic cardiomyopathy.
Does not change apical hypertrophic cardiomyopathy management; single-case data leave open shared histopathology with classic forms.
Whether apical hypertrophic cardiomyopathy is a variant of classic hypertrophic cardiomyopathy or a separate entity is controversial. This is a case report of an apical hypertrophic cardiomyopathy. The patient was a 67-year-old man associated with giant negative T waves in electrocardiogram and asymmetric apical hypertrophy on echocardiogram. He died of liver cirrhosis and liver cell carcinoma. At necropsy the heart showed apical hypertrophy grossly and extensive disarray of myocardial fibers near the apex of the left ventricle histologically. The necropsy findings were indistinguishable from those of classic hypertrophic cardiomyopathy. This suggests that apical hypertrophic cardiomyopathy is a variant of hypertrophic cardiomyopathy.
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Sumino et al. (1985) conducted a case report in Apical hypertrophic cardiomyopathy (n=1). Necropsy and histological examination was evaluated on Histological characteristics of the myocardium. Necropsy of a patient with apical hypertrophic cardiomyopathy revealed extensive myocardial disarray and fibrosis near the apex, suggesting it is a variant of classic hypertrophic cardiomyopathy.
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