Key result
Dystrophic mouse skeletal muscle microsomes show lower Ca2+ transport capacity than controls.
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Reduced Ca2+ transport in dystrophic mouse microsomes may contribute to pathology; leaves open translation to human muscular dystrophy.
The Ca2+ transport capacity of microsomes isolated from skeletal muscles of genetically dystrophic mice was significantly less than that of the control.
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A. Martonosi (1968) studied this question. Microsomes isolated from skeletal muscles of genetically dystrophic mice demonstrated significantly lower Ca2+ transport capacity compared to controls.
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