Why the study?
Several methods are used to prevent post-mastectomy pain, but the efficacy of ultrasound-guided pectoral nerves blocks for post-operative analgesia required evaluation.
Does preoperative ultrasound-guided Pectoral nerves block improve post-operative analgesia in adult female patients undergoing modified radical mastectomy?
Comparison
Preoperative Pecs blocks plus general anesthesia vs general anesthesia only
Design
Randomized controlled trial
Follow-up
24 hours
Key result
Preoperative ultrasound-guided Pectoral nerves blocks significantly reduced post-operative VAS scores and 24-hour nalbuphine consumption compared to general anesthesia alone.
Authors
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Supports routine Pecs block use for mastectomy analgesia; confirms RCT-level benefit of regional adjuncts in breast surgery.
RCT (n=40)
Randomly assigned
Does preoperative ultrasound-guided Pectoral nerves block improve post-operative analgesia in adult female patients undergoing modified radical mastectomy?
Ultrasound-guided Pecs blocks combined with general anesthesia significantly reduce post-operative pain and opioid consumption compared to general anesthesia alone in patients undergoing modified radical mastectomy.
Younis et al. (2021) conducted an RCT in Breast cancer (n=40). Pectoral nerves blocks (Pecs I and Pecs II) vs. General anesthesia only was evaluated on VAS score and total dose of nalbuphine consumption in 24 hours post-operative. Preoperative ultrasound-guided Pectoral nerves blocks significantly reduced post-operative VAS scores and 24-hour nalbuphine consumption compared to general anesthesia alone.
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