Predicting hyperlipidemia and hypothyroid severity using inflammation and oxidative stress markers in a prospective study

The aim of this research was to explore the impact of dysthyroidism on lipid metabolism by examining lipid profile parameters in individuals diagnosed with dysthyroidism. A case-control study was conducted to compare the lipid profiles of patients with dysthyroidism to those without it. The study used convenient sampling to select newly diagnosed dysthyroidism cases from two diagnostic centers: Sarita Diagnostic Centre in Shamli and Dr. Lal Pathlabs in Delhi. A total of 569 hyperlipidemia cases and 454 dysthyroidism cases were included in the analysis. Blood samples were collected from all participants to assess various lipid profile indicators such as total serum cholesterol, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL). The goal was to examine any correlations between abnormal lipid levels and thyroid dysfunction. Additionally, to investigate potential cardiovascular implications, participants underwent 2D echocardiography to evaluate the risk of coronary heart disease (CHD) in relation to dysthyroidism. This method offered valuable insights into the connection between thyroid disorders, lipid metabolism, and heart health. The findings of this study could contribute significantly to understanding how thyroid dysfunction might affect lipid levels and its potential association with cardiovascular diseases.