Key result
Biomedlab IVAD shows feasibility in calves with survival up to 21 days despite mechanical failures.
Why the study?
Does the Biomedlab(R) IVAD demonstrate durability and safety in a calf model?
Does the Biomedlab(R) IVAD demonstrate durability and safety in a calf model?
The newly developed Biomedlab(R) IVAD was feasible for implantation and showed no device-related thrombosis in a calf model, though mechanical issues require correction before long-term testing.
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Feasibility in calves supports device iteration; leaves open long-term durability and clinical translation pending mechanical refinements.
Chang et al. (2008) studied Preclinical testing of ventricular assist device (n=5). Biomedlab(R) electro-mechanical implantable ventricular assist device (IVAD) was evaluated on Durability, safety, and hematologic effect. Implantation of the Biomedlab IVAD in 5 calves demonstrated feasibility with survival up to 21 days and no device-related thrombosis, despite 3 mechanical failures.
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