Key result
Propofol cuts spinal anesthesia recovery time by ~8 minutes vs midazolam and improves higher mental function.
Why the study?
Does propofol improve recovery time compared to midazolam in patients receiving sedation during spinal anaesthesia for orthopaedic surgery?
Population
20 patients scheduled for orthopaedic surgery under spinal anaesthesia
Comparison
1% propofol by intravenous infusion at a rate… vs 0.1% midazolam by intravenous infusion at a rate…
Design
Other
Follow-up
up to 2 hours after surgery
Authors
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May support propofol for faster sedation recovery in spinal anaesthesia; leaves open randomized confirmation.
RCT (n=20)
Does propofol improve recovery time compared to midazolam in patients receiving sedation during spinal anaesthesia for orthopaedic surgery?
Absolute Event Rate: 2% vs 10%
Propofol provides significantly faster recovery of consciousness and higher mental function compared to midazolam when used for sedation during spinal anaesthesia.
Wilson et al. (1988) conducted an RCT in Orthopaedic surgery under spinal anaesthesia (n=20). Propofol (1%) vs. Midazolam (0.1%) was evaluated on Recovery time (ability to open eyes and recall date of birth). Propofol infusion provided significantly more rapid recovery (2 vs 10 minutes) and better recovery of higher mental function compared to midazolam in patients undergoing spinal anaesthesia.
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