Key result
PGA/PLA tissue engineering shows potential to overcome limitations of current prosthetic and biologic heart valves.
Design
Review
Authors
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May address growth limitations in pediatric valves; hypothesis-generating and requires preclinical validation before any clinical consideration.
Tissue engineering using PGA/PLA co-polymers offers a potential pathway to overcome the limitations of current prosthetic and biologic heart valves, particularly the lack of growth potential in pediatric patients.
Stock et al. (2001) conducted a review in Heart valve replacement. Tissue engineering using PGA/PLA co-polymers was evaluated. Tissue engineering using synthetically produced polyglycolic acid/polylactid acid co-polymers offers a potential pathway to overcome the limitations of current prosthetic and biologic heart valves.
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