Key result
Pulsatile flow eliminates flow reversal versus steady flow, matching clinical atherosclerotic shear stress patterns.
Population
Computational model of pulsatile flow of an incompressible, Newtonian fluid through a symmetric bifurcated…
Comparison
Numerical analysis solving three-dimensional… vs Steady flow at the same Reynolds number
Design
Preclinical
Authors
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Supports hemodynamic modeling of atherosclerosis; leaves open clinical translation without human validation.
Computational modeling of pulsatile flow in a bifurcation demonstrates that time-averaged shear stress regions correlate with clinically observed sites of atherosclerotic plaque formation.
Yung et al. (1997) studied this question. Pulsatile flow vs. Steady flow was evaluated on Flow characteristics including flow reversal regions, secondary flow, and shear stress. Pulsatile flow through a symmetric bifurcation eliminated flow reversal at the highest inlet Reynolds number compared to steady flow, with shear stress patterns matching clinical atherosclerotic sites.
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