Key result
Hydrogen clearance reliably measures capillary blood flow changes in experimental skeletal muscle and beating hearts.
Why the study?
Does the hydrogen clearance technique reliably measure capillary blood flow in experimental animals?
Population
Experimental animals (skeletal muscle and beating heart)
Comparison
Hydrogen clearance technique vs Various methods for introducing hydrogen and…
Design
Preclinical
Authors
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Validates hydrogen clearance for capillary flow in animal models; leaves open translation to human cardiovascular research.
Does the hydrogen clearance technique reliably measure capillary blood flow in experimental animals?
The hydrogen clearance technique is demonstrated to be a reliable method for measuring changes in capillary blood flow in experimental models.
Harrison et al. (1989) studied Measurement of capillary blood flow. Hydrogen clearance technique was evaluated on Measurement of capillary blood flow. A hydrogen clearance technique provided reliable and reproducible measurements of changes in capillary blood flow in skeletal muscle and the beating heart of experimental animals.
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