Population
Isolated gastrocnemius muscle of cats
Comparison
Xe133 clearance technique vs Directly metered blood flow (drop counter flow)
Design
Preclinical
Authors
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Xe133 clearance warrants caution with intramuscular use; leaves open its validity for human perfusion assessment.
The Xe133 clearance technique provides a reasonable estimate of local blood flow when administered intraarterially, but significantly underestimates flow when given intramuscularly.
Kjellmer et al. (1967) studied this question.
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