Key result
A 38-kD protein distributes in reticular skeletal muscle and exclusively in cardiac muscle containing transverse tubules.
Population
Vertebrate skeletal and cardiac muscle tissue
Design
Preclinical
Authors
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Hypothesis-generating in animal muscle; leaves open relevance to human cardiac T-tubule function.
The 38-kD protein is associated with transverse tubules in skeletal and cardiac muscle, providing insight into its structural and functional role.
Tidball et al. (1988) studied this question. Affinity purified, polyclonal antisera against 38-kD protein was evaluated on Distribution and biochemical properties of a 38-kD muscle protein. A 38-kD protein is distributed in a reticular pattern within cross-sectional skeletal muscle and is present only in cardiac muscle containing transverse tubules.
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