Silent Myocardial Ischemia and Infarction: Insights from the Framingham Study
Key result
Unrecognized MIs are linked to similar 30-year risks of death, HF, or stroke as recognized MIs.
Why the study?
Do unrecognized myocardial infarctions have a similar prognosis to recognized infarctions in terms of death, heart failure, or stroke?
Population
Participants in the Framingham Study who experienced myocardial infarctions over a 30-year period
Design
Cohort
Follow-up
30 years
Authors
Discussion
Loading...
Member takes
Implication
Unrecognized MIs carry equivalent long-term risks; leaves open whether routine ECG screening improves outcomes in asymptomatic adults.
Study Design
Type
Cohort
Structured PICO
Do unrecognized myocardial infarctions have a similar prognosis to recognized infarctions in terms of death, heart failure, or stroke?
P
Population
Participants in the Framingham Study followed over 30 years with routine biennial electrocardiographic examinations.
C
Comparator
Recognized myocardial infarctions
O
Outcome
Eventual death, heart failure, or strokeshard clinical
Unrecognized myocardial infarctions are common and carry a prognosis as serious as symptomatic infarctions, highlighting the importance of routine electrocardiographic screening.
Cite This Study
William B. Kannel (1986) conducted a cohort in Myocardial infarction. Unrecognized myocardial infarction vs. Recognized myocardial infarction was evaluated on Eventual death, heart failure, or strokes. Unrecognized myocardial infarctions (35% of infarcts in women, 28% in men) were as likely as recognized infarcts to result in eventual death, heart failure, or strokes over 30 years.