Key result
Hypoxemic exercise induces myocardial lactate release, covering ~1% of cardiac energy demand via anaerobic metabolism.
Why the study?
Does prolonged exercise under hypoxaemia induce myocardial lactate release compared to normoxaemia in healthy men?
Population
12 healthy men
Comparison
Prolonged exercise breathing 12% O2 vs Prolonged exercise breathing air
Design
Other, Order of normoxaemia/hypoxaemia was varied between subjects
Follow-up
30 min per exercise condition
Authors
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Should not change exercise guidance in hypoxia; leaves open relevance to patients with cardiopulmonary disease.
Does prolonged exercise under hypoxaemia induce myocardial lactate release compared to normoxaemia in healthy men?
Prolonged exercise under severe hypoxaemia induces a small degree of myocardial anaerobic metabolism, despite compensatory increases in coronary blood flow.
Kaijser et al. (1993) studied Healthy (n=12). Prolonged exercise breathing 12% O2 vs. Prolonged exercise breathing air was evaluated on Myocardial lactate release. Prolonged exercise breathing 12% O2 induced a myocardial lactate release of approximately 90 mumol/min, indicating that about 1% of cardiac energy demand is covered by anaerobic metabolism.
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