Key result
Hypoxic interval training improves autonomic function, arterial stiffness, endothelial function, and aerobic capacity versus normoxia.
Why the study?
The study was conducted to verify the effects of interval training under hypoxia on the autonomic nervous system and arterial and hemorheological function in healthy women.
Does interval training under hypoxia improve autonomic nervous system function, arterial stiffness, and hemorheological function in healthy women compared to normoxic training?
RCT (n=20)
Does interval training under hypoxia improve autonomic nervous system function, arterial stiffness, and hemorheological function in healthy women compared to normoxic training?
p-value: p=< 0.05
Interval training under hypoxia for 6 weeks significantly improves autonomic nervous system function, arterial stiffness, and aerobic performance in healthy women compared to normoxic training.
Should not yet change practice in healthy women; hypothesis-generating for hypoxic training benefits.
Purpose: The present study verified the effects of interval training under hypoxia, a novel exercise modality for health promotion, on the autonomic nervous system (ANS) and arterial and hemorheological function in healthy women. Methods: Twenty healthy Korean women (age: 19– 29 [24.85 ± 3.84] years) were equally assigned to interval normoxic training (INT, n = 10; residing and training under normoxia) and interval hypoxic training (IHT, n = 10; residing under normoxia and training under 526 mmHg hypobaric hypoxia) groups. All participants performed 90-min of training sessions composed of 15-min of warm-up, 60-min of interval training, and 15-min of cool-down. The interval training sessions composed of 10 repetitions of interval exercise using a treadmill (5 min of exercise corresponding to 90– 95% maximal heart rate [HR] and 1 min of rest). The training was performed 3 days per week for 6 weeks. All participants underwent body composition, HR variability, brachial-ankle pulse wave velocity, flow-mediated dilation (FMD), red blood cell (RBC) deformability and aggregation, and maximal oxygen uptake (VO 2 max) measurements before and after training. Results: There were no significant differences in body composition between the groups. The IHT group showed a significant improvement in the ANS function (root mean square of successive differences, high frequency, and low frequency/high frequency ratio), arterial stiffness, arterial endothelial function (FMD), hemorheological function (RBC deformability and aggregation), and aerobic performance (VO 2 max) compared with the INT (all p < 0.05). Conclusion: In comparison with the interval training under normoxia, the interval training under hypoxia is a novel and effective exercise modality for promoting aerobic performance with the ANS and arterial and hemorheological function in healthy women.
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A 2022 study conducted an RCT in Healthy (n=20). Interval hypoxic training vs. Interval normoxic training was evaluated on Autonomic nervous system function, arterial stiffness, arterial endothelial function, hemorheological function, and aerobic performance (p=< 0.05). Interval training under hypoxia significantly improved autonomic nervous system function, arterial stiffness, endothelial function, and aerobic capacity compared to normoxic training (all p<0.05).
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