Key result
Iron, hydration, and a beta-blocker resolve anemia-induced systolic anterior motion and dynamic intraventricular obstruction.
Case Report (n=1)
Anemia can induce hyperdynamic left ventricular contraction leading to systolic anterior motion of the mitral valve and dynamic intraventricular obstruction, which can be successfully managed with hydration, beta-blockers, and anemia correction.
Anemia may induce reversible SAM and obstruction post-CABG; case report leaves open prospective validation before practice change.
Dynamic left ventricular (LV) outflow tract obstruction is a characteristic feature of hypertrophic cardiomyopathy; however, it can also occur in association with hyperdynamic LV contraction and/or changes in the cardiac loading condition, even in a structurally normal or near-normal heart. Here, we report a case of anemia-induced systolic anterior motion of the mitral valve and the resultant intraventricular obstruction in a patient who underwent coronary artery bypass grafting and suffered from anemia associated with recurrent gastrointestinal bleeding.
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Mun et al. (2013) conducted a case report in Exertional dyspnea due to anemia-induced systolic anterior motion of the mitral valve and dynamic left ventricular outflow tract obstruction (n=1). Oral iron supplement, oral hydration, and beta-blocker (bisoprolol) was evaluated on Resolution of heart failure symptoms and echocardiographic abnormalities. Treatment with oral iron supplementation, hydration, and a beta-blocker successfully resolved anemia-induced systolic anterior motion of the mitral valve and dynamic intraventricular obstruction.
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