It Is Not About the Bike, It Is About the Pedaling

In Brief Forced exercise has resulted in neuroprotective effects and improved motor function in animal studies. These promising results have not yet been translated fully to humans with Parkinson's disease (PD), as traditional exercise interventions have not yielded global improvements in function. A novel forced exercise intervention is described that has resulted in improved motor function and central nervous system function in PD patients. A novel forced-exercise intervention is described, resulting in improved global motor function and cortical activation in patients with Parkinson's disease.