In the determination of sizes and concentrations of nanoparticles (NPs), single particle-inductively coupled plasma-mass spectrometry (SP-ICP-MS) suffers uncertainties in the transport efficiency of nebulized liquid droplets of NPs. Many potential factors such as primary particle sizes, concentrations, and ionic components of metal NPs could influence transport efficiency and accuracy of the SP-ICP-MS analysis.
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Zhang et al. (2015) studied this question.
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