Herpes-simplex virus type-1 (HSV-1) represents a life persistent infection. It is primarily treated by acyclovir however resistant strains are increasing which urged the development of new treatment strategies. Zinc nanoparticles (ZNPs) based therapeutics is gaining a lot of attention. The current study aims to investigate variable physicochemical interactions of ZNPs bearing different chemical moieties and surface properties with the cell receptors and the viral particles, and their effect on reducing HSV-1 infection.
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Farouk et al. (2018) studied this question.
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