Key result
Retroperitoneal fat area measurement predicts metabolic syndrome risk in ~96% of patients undergoing adrenalectomy.
Why the study?
Does retroperitoneal fat area measurement correlate with metabolic syndrome in patients undergoing adrenalectomy?
Cross-Sectional (n=61)
No
Does retroperitoneal fat area measurement correlate with metabolic syndrome in patients undergoing adrenalectomy?
Effect estimate: r=0.894
p-value: p=0.0001
Retroperitoneal fat area measured by CT is strongly correlated with metabolic syndrome and can accurately predict its presence in patients undergoing adrenalectomy.
Supports MetS prediction by RFA on CT in adrenalectomy patients; hypothesis-generating and requires prospective validation before clinical adoption.
BACKGROUND: Visceral obesity is one of the main components of the metabolic syndrome (MetS). The retroperitoneal fat area (RFA) is part of the intraabdominal adipose mass. The aim of this clinical trial was to determine whether there is an association between the RFA measurement and MetS components in patients undergoing laparoscopic lateral transabdominal adrenalectomy. METHODS: The study population consisted of 61 consecutive patients who underwent laparoscopic adrenalectomy between January 2007 and June 2010 at the Istanbul Faculty of Medicine. Anthropometric, demographic, and biochemical parameters as well as cardiometabolic risk factors were recorded. The RFA was calculated using computed tomography. RESULTS: The mean body mass index, waist circumference, and RFA in patients with MetS was significantly higher than that of the patients without MetS. There were positive correlations between RFA and central obesity (r=0.675, p=0.0001) and MetS (r=0.894, p=0.0001). The strongest correlation was observed between RFA and MetS. According to receiver operating characteristic analysis, RFA measurement correctly predicted MetS risk in 96% of patients and failed in only 4%. CONCLUSIONS: Our findings indicate that measurement of the RFA may provide a safe, easy assessment of its metabolic risk.
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Ersöz et al. (2011) conducted a cross-sectional in Metabolic syndrome (n=61). Retroperitoneal fat area (RFA) measurement was evaluated on Metabolic syndrome (MetS) (r=0.894, p=0.0001). Retroperitoneal fat area measurement strongly correlated with metabolic syndrome (r=0.894, p=0.0001) and correctly predicted metabolic syndrome risk in 96% of patients undergoing adrenalectomy.
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