Key result
Abnormal maximal treadmill stress test predicts ~23% CHD risk, outperforming the double Master's test.
Why the study?
Does the maximal treadmill stress test predict subsequent coronary heart disease better than the double Master's test in normal subjects?
Cohort (n=100)
Does the maximal treadmill stress test predict subsequent coronary heart disease better than the double Master's test in normal subjects?
Absolute Event Rate: 23.1% vs 1.1%
The maximal treadmill stress test is a superior predictor of future coronary heart disease compared to the double Master's test in normal subjects.
May aid CHD prediction in asymptomatic adults over double Master's test; leaves open incremental value versus modern risk tools.
One hundred normal subjects who had a double Master's test and a maximal treadmill stress test (MTST) were clinically evaluated 30 months later. Ninety-nine of these 100 subjects (99%) had a follow-up treadmill test at 30 months. One of four subjects (25%) with initially an abnormal double Master's test developed coronary heart disease within 30 months. Three of 96 subjects (3.1%) with initially a normal double Master's test developed coronary heart disease within 30 months. Three of 13 subjects (23.1%) with initially an abnormal MTST developed coronary heart disease within 30 months. One of 87 subjects (1.1%) with initially a normal MTST developed coronary heart disease within 30 months. The MTST correlated better than the double Master's test in predicting subsequent coronary heart disease.
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Wilbert S. Aronow (1973) conducted a cohort in Normal subjects (n=100). Abnormal maximal treadmill stress test (MTST) vs. Normal MTST was evaluated on Development of coronary heart disease. An abnormal maximal treadmill stress test predicted subsequent coronary heart disease in 23.1% of subjects versus 1.1% with a normal test, correlating better than the double Master's test.
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