What is the clinical evidence from this study?

Study design: Observational. Population: Hemodialysis (hypotension-prone vs hemodynamically stable) (n=20). Intervention: Hypotension-prone status vs. Hemodynamically stable status. Primary outcome: Sympatho-vagal balance index (ratio between low and high frequency range integrals).

What does this research mean for the field?

Hypotension-prone hemodialysis patients exhibit an impaired autonomic reflex response to hypovolemia during dialysis, failing to show the normal progressive increase in sympatho-vagal balance. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1995The International Journal of Artificial Organs

Autonomic Nervous Function and Blood Volume Monitoring during Hemodialysis

View Full Paper

Ask AI

Bookmark

Key result

Hypotension-prone hemodialysis patients exhibit impaired autonomic reflexes with a ~79% lower sympatho-vagal balance index.

n=20

Why the study?

Does the autonomic reflex response to hypovolemia differ between hypotension-prone and hemodynamically stable patients during hemodialysis?

Population

20 patients undergoing hemodialysis, consisting of 10 hypotension-prone patients and 10 hemodynamically…

Comparison

Hemodialysis with monitoring of autonomic reflex… vs Hemodynamically stable patients compared to…

Design

Cohort

Follow-up

210 minutes

Authors

GEG. EnzmannOspedale Maggiore FBFrancesco BiancoPediatric / Congenital Cardiology FPF. PaoliniApollo Hospitals

Discussion

Member takes

Implication

Impaired autonomic response may flag intradialytic hypotension risk; hypothesis-generating and leaves open whether modulation improves outcomes.

Study Design

Type

Observational (n=20)

Structured PICO

Does the autonomic reflex response to hypovolemia differ between hypotension-prone and hemodynamically stable patients during hemodialysis?

Population

20 hemodialysis patients, comprising 10 hypotension-prone and 10 hemodynamically stable individuals, evaluated for autonomic reflex response during treatment.

Exposure

Hemodialysis with monitoring of autonomic reflex response to hypovolemia via spectral analysis of heart rate variability (SAHRV).

Comparator

Hemodynamically stable patients (group B) compared to hypotension-prone patients (group A).

Outcome

Sympatho-vagal balance index (ratio between the integrals of the spectrum in the low 0.02-0.15 Hz and high 0.2-0.35 Hz frequency ranges) measured up to 210 minutes during hemodialysis.surrogate

Spectral analysis of heart rate variability demonstrates that hypotension-prone patients have an impaired autonomic reflex response to hypovolemia during hemodialysis.

Cite This Study

Enzmann et al. (1995) conducted an observational in Hemodialysis (hypotension-prone vs hemodynamically stable) (n=20). Hypotension-prone status vs. Hemodynamically stable status was evaluated on Sympatho-vagal balance index (ratio between low and high frequency range integrals). Hypotension-prone hemodialysis patients had an impaired autonomic reflex response to hypovolemia, with a lower sympatho-vagal balance index at 90 minutes (3.7 vs 17.9 in stable patients).

synapsesocial.com/papers/6aa744bc988cce70a1e57ef3 https://doi.org/10.1177/039139889501800905

View Full Paper

Ask AI

Bookmark

Implication

Impaired autonomic response may flag intradialytic hypotension risk; hypothesis-generating and leaves open whether modulation improves outcomes.

Autonomic Nervous Function and Blood Volume Monitoring during Hemodialysis

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Autonomic Nervous Function and Blood Volume Monitoring during Hemodialysis

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider