Why the study?
What are the sequential changes in autonomic nervous system activity during intradialytic hypotension in hemodialysis patients?
Population
19 patients undergoing hemodialysis, including those prone and not prone to develop intradialytic hypotension.
Comparison
Hemodialysis sessions complicated by severe… vs Hemodialysis sessions not complicated by…
Design
Cohort
Follow-up
During hemodialysis sessions
Authors
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Supports Bezold-Jarisch reflex activation during intradialytic hypotension; hypothesis-generating for autonomic-targeted interventions in hemodialysis.
What are the sequential changes in autonomic nervous system activity during intradialytic hypotension in hemodialysis patients?
Sudden intradialytic hypotension is caused by activation of the sympatho-inhibitory cardiodepressor reflex (Bezold-Jarisch reflex), characterized by decreased sympathetic and increased parasympathetic nervous system activity.
Barnas et al. (1999) studied this question.
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