Key result
Prosthetic valve replacement for rheumatic heart disease yields ~86% long-term survival in Nigeria.
Population
26 indigent patients with rheumatic valvular disease, mean age 26.69 ± 9.87 years, 73.1% female, undergoing…
Design
Cohort
Follow-up
83.0 ± 27.9 months (for survivors)
Authors
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Anticoagulant complications predominate after mechanical valve replacement in this setting; hypothesis-generating for bioprosthetic preference in young females, needs prospective confirmation.
Observational (n=26)
Yes
In young, indigent Nigerian patients undergoing predominantly mechanical valve replacement for rheumatic heart disease, late complications were primarily anticoagulant-related, suggesting bioprosthetic valves may be preferable for females of childbearing age in low-resource settings.
Nwiloh et al. (2015) conducted an observational in Rheumatic heart disease (n=26). Prosthetic valve replacement was evaluated on 10-year survival. In 26 patients undergoing prosthetic valve replacement for rheumatic heart disease in Nigeria, operative mortality was 11.5% and 10-year survival was 86.0%.
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