Key result
RHD valve surgery is linked to ~5-fold higher odds of Aboriginal or Torres Strait Islander status.
Why the study?
What are the demographic and clinical factors associated with the choice of surgical treatment for advanced rheumatic heart disease in Australia?
Observational (n=17,227)
Yes
What are the demographic and clinical factors associated with the choice of surgical treatment for advanced rheumatic heart disease in Australia?
Odds Ratio: 5.1 (95% CI 2.67–9.8)
Absolute Event Rate: 12.6% vs 1%
p-value: p=<0.001
In Australia, RHD valve surgery is more common in young, female, and Indigenous patients, with an increasing trend in the use of bioprosthetic valves over time.
Highlights Indigenous disparities in RHD surgery burden; supports targeted prevention efforts while leaving mechanisms open for prospective study.
BACKGROUND: Globally, rheumatic heart disease (RHD) remains an important cause of heart disease. In Australia it particularly affects older non-Indigenous Australians and Aboriginal Australians and/or Torres Strait Islander peoples. Factors associated with the choice of treatment for advanced RHD remain variable and poorly understood. METHODS: The Australian and New Zealand Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database was analysed. Demographics, co-morbidities, pre-operative status and valve(s) affected were collated and associations with management assessed. RESULTS: Surgical management of 1384 RHD and 15843 non-RHD valve procedures was analysed. RHD patients were younger, more likely to be female and Indigenous Australian, to have atrial fibrillation (AF) and previous percutaneous balloon valvuloplasty (PBV). Surgery was performed on one valve in 64.5%, two valves in 30.0% and three valves in 5.5%. Factors associated with receipt of mechanical valves in RHD were AF (OR 2.69) and previous PBV (OR 1.98) and valve surgery (OR 3.12). Predictors of valve repair included being Indigenous (OR 3.84) and having fewer valves requiring surgery (OR 0.10). Overall there was a significant increase in the use of mitral bioprosthetic valves over time. CONCLUSIONS: RHD valve surgery is more common in young, female and Indigenous patients. The use of bioprosthetic valves in RHD is increasing. Given many patients are female and younger, the choice of valve surgery and need for anticoagulation has implications for future management of RHD and related morbidity, pregnancy and lifestyle plans.
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Russell et al. (2014) conducted an observational in Valvular heart disease (n=17,227). Rheumatic heart disease vs. Non-rheumatic heart disease was evaluated on Aboriginal and/or Torres Strait Islander status (OR 5.10, 95% CI 2.67-9.80, p=<0.001). Patients undergoing valve surgery for rheumatic heart disease were significantly more likely to be Aboriginal and/or Torres Strait Islander compared to those with non-rheumatic valve disease (12.6% vs 1.0%, OR 5.10).
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