Comparison of post ablation left atrial volume index versus left atrial reverse remodeling for prognostic events in persistent atrial fibrillation

Figures

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  Fig. 1. Study diagram. AF atrial fibrillation, LARR left atrial reverse remodeling, LAVI left atrial volume index, MACE major adverse cardiovascular event.

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  Fig. 2. Kaplan–Meier curves comparing the cumulative incidence of MACE across tertiles A Comparison of post-ablation LAVI, B comparison of post-ablation LARR. Each plot is expressed as the cumulative incidence of an event with a 95% confidence interval. Asterisks indicate statistical significance (*p < 0.05). LARR left atrial reverse remodeling, LAVI left atrial volume index, MACE major adverse cardiovascular event.

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  Fig. 3. Kaplan–Meier curves comparing the cumulative incidence of freedom from arrhythmic recurrence across tertiles (A) Comparison of post-ablation LAVI, (B) Comparison of post-ablation LARR. Each plot expressed the cumulative incidence of freedom from the event with a 95% confidence interval (CI). Asterisks indicate statistical significance (*p < 0.05). LARR left atrial reverse remodeling, LAVI left atrial volume index.

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  Fig. 4. The association between post-ablation LAVI and LARR A Correlation between post-ablation LAVI and LARR. B Post-ablation LARR distribution by post-ablation LAVI tertiles. The purple line represents a positive linear correlation between Post-ablation LAVI and LARR, with a 95% confidence interval. LARR left atrial reverse remodeling; LAVI left atrial volume index.

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  Fig. 5. Risk trend for MACE across the post-ablation LAVI and LARR A Across post-ablation LAVI values, B Across post-ablation LARR values. Each plot is expressed as an adjusted HR with a 95% confidence interval. The HR was adjusted for age, female sex, pre-ablation left ventricular ejection fraction, arrhythmic recurrence at 3 months post-ablation, pre-ablation brain natriuretic peptide level, history of heart failure hospitalization, pre-ablation estimated glomerular filtration rate, and any structural heart disease. HR hazard ratio, LARR left atrial reverse remodeling, LAVI left atrial volume index, MACE major adverse cardiovascular event.

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  Fig. 6. Graphical abstract. AF atrial fibrillation, CA catheter ablation, CV cardiovascular, LARR left atrial reverse remodeling, LAVI left atrial volume index, MACE major adverse cardiovascular event.