Key result
Trazodone overdose linked to reversible hypotension and QTc prolongation peaking at 586 ms.
Why the study?
Reports of trazodone overdose leading to QTc prolongation and fatal arrhythmias are few, highlighting the need to recognize rare but potentially fatal toxicities.
Case Report (n=1)
No
Trazodone overdose can manifest with clinically significant hypotension and progressive QTc prolongation requiring intensive care monitoring and supportive management.
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Reports of trazodone overdose QTc prolongation may warrant ECG caution; leaves open true arrhythmic incidence.
Mohan et al. (2023) conducted a case report in Trazodone overdose (n=1). Trazodone overdose was evaluated on QTc prolongation and hypotension. Trazodone overdose of 500 mg in a 45-year-old female led to significant hypotension and progressive QTc prolongation peaking at 586 ms, which resolved with supportive care.
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