Key result
Relapse within six months post-ECT is not associated with long-term depression recurrence.
Why the study?
Does relapse within 6 months post-ECT influence the long-term recurrence of depression in patients with pharmacotherapy treatment failure?
Population
26 depressed patients responsive to ECT with intensive pre-ECT pharmacotherapy treatment failure who…
Comparison
Group without relapse within 6 months post-ECT vs Group with relapse within 6 months post-ECT
Design
Cohort
Follow-up
mean 6.8 years (range 4 to 8 years)
Authors
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High long-term recurrence after ECT is not linked to early relapse; leaves open optimal maintenance approaches in treatment-resistant depression.
Cohort (n=26)
Does relapse within 6 months post-ECT influence the long-term recurrence of depression in patients with pharmacotherapy treatment failure?
In patients with depression responsive to ECT, long-term recurrence is high (42.3%) and is not influenced by whether they relapsed within the first 6 months post-ECT.
Beusekom et al. (2007) conducted a cohort in Depression (n=26). Relapse within 6 months post-ECT vs. No relapse within 6 months post-ECT was evaluated on Recurrence of depression up to 8 years later. Relapse within 6 months after terminating ECT did not significantly influence the long-term recurrence of depression, which occurred in 42.3% of patients over a mean follow-up of 6.8 years.