Key result
Insulin-dependent diabetes links to ~58% higher five-year mortality vs no diabetes after STEMI PCI.
Why the study?
Does diabetic status (IDDM vs NIDDM vs no DM) affect long-term mortality in patients with STEMI treated with primary PCI?
Cohort (n=2,087)
No
Does diabetic status (IDDM vs NIDDM vs no DM) affect long-term mortality in patients with STEMI treated with primary PCI?
Hazard Ratio: 1.58 (95% CI 1.07–2.32)
Absolute Event Rate: 32.7% vs 18%
p-value: p=0.02
In patients undergoing primary PCI for STEMI, insulin-dependent diabetes mellitus is an independent predictor of 5-year mortality, whereas non-insulin-dependent diabetes is not.
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IDDM marks higher 5-year mortality risk after primary PCI for STEMI; leaves open whether insulin dependence warrants targeted interventions in prospective studies.
Zlatanovic et al. (2015) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=2,087). Insulin-dependent diabetes mellitus (IDDM) vs. No diabetes mellitus was evaluated on Five-year mortality (HR 1.58, 95% CI 1.07-2.32, p=0.02). Insulin-dependent diabetes mellitus was an independent predictor of five-year mortality (HR 1.58) compared to patients without diabetes following primary PCI for STEMI.
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