What is the clinical evidence from this study?

Study design: Observational. Population: Acute cardiac death of unknown etiology (Pokkuri disease) (n=283). Intervention: Acute cardiac death of unknown etiology. Primary outcome: Characteristics and circumstances of acute cardiac death of unknown etiology.

What does this research mean for the field?

Acute cardiac death of unknown etiology in Japan predominantly affects apparently healthy young males who die abruptly during nighttime sleep without identifiable causes on autopsy or biochemical testing. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1962Japanese Heart JournalOpen Access

Acute Cardiac Death of Unknown Etiology A Preliminary Report

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Key result

Acute cardiac death of unknown etiology predominantly strikes apparently healthy young males abruptly during sleep.

n=283

Population

283 cases of 'acute cardiac death of unknown etiology' autopsied at the Tokyo Medical Examiner Office…

Design

Case_series

Authors

TKTachio KobayashiTokyo Medical University YIYoshio ItoTokyo Medical University TKTerutomo KajiharaUniversity of Tokyo Hospital

Discussion

Member takes

Implication

Does not warrant practice changes in sudden death evaluation; leaves open neurohumoral involvement in unexplained nocturnal arrest among young males.

Study Design

Type

Observational (n=283)

Structured PICO

Population

283 cases of acute cardiac death of unknown etiology autopsied in Tokyo between 1959 and 1961, predominantly affecting young, apparently healthy males who died during sleep.

Outcome

Causative mechanism of acute cardiac death of unknown etiology

This early autopsy study of Pokkuri disease in Japan suggests a role for the neurohumoral system in sudden unexplained nocturnal death in young males.

Limitations

The exact mechanism and etiology of the acute cardiac deaths remain uncertain.
The investigation was limited to the Tokyo area, so regional differences could not be assessed.

Cite This Study

Kobayashi et al. (1962) conducted an observational in Acute cardiac death of unknown etiology (Pokkuri disease) (n=283). Acute cardiac death of unknown etiology was evaluated on Characteristics and circumstances of acute cardiac death of unknown etiology. Acute cardiac death of unknown etiology in Japan predominantly affected apparently healthy young males who died abruptly during sleep at night, with autopsy revealing no definitive cause.

synapsesocial.com/papers/6aa7709867c2e25ec0038c25 https://doi.org/10.1536/ihj.3.442

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January 1, 1962Japanese Heart JournalOpen Access

Acute Cardiac Death of Unknown Etiology A Preliminary Report

View Full Paper

Ask AI

Bookmark

Key result

Acute cardiac death of unknown etiology predominantly strikes apparently healthy young males abruptly during sleep.

n=283

Population

283 cases of 'acute cardiac death of unknown etiology' autopsied at the Tokyo Medical Examiner Office…

Design

Case_series

Authors

TKTachio KobayashiTokyo Medical University YIYoshio ItoTokyo Medical University TKTerutomo KajiharaUniversity of Tokyo Hospital

Discussion

Member takes

Implication

Does not warrant practice changes in sudden death evaluation; leaves open neurohumoral involvement in unexplained nocturnal arrest among young males.

Study Design

Type

Observational (n=283)

Structured PICO

Population

283 cases of acute cardiac death of unknown etiology autopsied in Tokyo between 1959 and 1961, predominantly affecting young, apparently healthy males who died during sleep.

Outcome

Causative mechanism of acute cardiac death of unknown etiology

This early autopsy study of Pokkuri disease in Japan suggests a role for the neurohumoral system in sudden unexplained nocturnal death in young males.

Limitations

The exact mechanism and etiology of the acute cardiac deaths remain uncertain.
The investigation was limited to the Tokyo area, so regional differences could not be assessed.

Cite This Study

synapsesocial.com/papers/6aa7709867c2e25ec0038c25 https://doi.org/10.1536/ihj.3.442

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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