Key result
Adapted Ross procedure using Ozaki technique yields excellent aortic and pulmonary hemodynamics at 4 months.
Why the study?
Unavailability of homografts for pulmonary valve replacement limits the wider utilization of the Ross procedure for aortic valve disease.
Does pulmonary valve neo-reconstruction using the Ozaki technique in an adapted Ross procedure provide acceptable hemodynamic outcomes in a patient with severe aortic regurgitation?
Case Report (n=1)
Does pulmonary valve neo-reconstruction using the Ozaki technique in an adapted Ross procedure provide acceptable hemodynamic outcomes in a patient with severe aortic regurgitation?
The modified Ross procedure with Ozaki neo-cuspidalization for the pulmonary valve provides a feasible alternative for aortic valve replacement when pulmonary homografts are unavailable.
May offer workaround for homograft shortage in Ross procedure; leaves open durability and applicability pending larger studies.
Background: Aortic valve damage is the most common valvular heart disease in developed countries. The Ross procedure is an alternative to the aortic valve replacement with a prosthesis, providing a longer survival without reoperation and without the need for anticoagulation therapy. The unavailability of homografts for the pulmonary valve replacement is one of the limiting factors for a more common utilization of this therapeutic method. Case summary: This case report presents a 35-year-old Caucasian male with a bicuspid aortic valve and severe aortic regurgitation. The patient underwent the Ross procedure with the stabilization of the aortic ring and sinotubular junction. A tubular prosthesis was created from the bovine pericardium, into which three neo-cusp valves were fashioned from autologous pericardium. The new pulmonary conduit was sutured distally to the distal pulmonary trunk and proximally to the right ventricular outflow tract. Four months post-operatively, the follow-up echocardiographic examination documented that the valve in the aortic position had no regurgitation, a maximum velocity of 1.25 m/s, and a peak gradient of 6.25 mmHg. The valve in the pulmonary position showed a trace regurgitation and mean pressure gradient of 13 mmHg. Discussion: The combination of the modified Ross procedure with neo-cuspidalization according to Ozaki for a new pulmonary valve thus offers hope for an extended survival without reoperation in paediatric and non-elderly adult patients with an aortic valve dysfunction. This technique is additionally applicable by cardiac surgery centres without access to pulmonary homografts.
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Kolesár et al. (2025) conducted a case report in Bicuspid aortic valve and severe aortic regurgitation (n=1). Ross procedure with pulmonary valve neo-reconstruction using the Ozaki technique was evaluated on Echocardiographic valve function. An adapted Ross procedure using the Ozaki technique for pulmonary valve neo-reconstruction resulted in excellent aortic and pulmonary valve hemodynamics at 4 months post-operatively.
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