Key result
Arterial hypertension in women with triple negative breast cancer was associated with lower baseline global longitudinal strain compared to normal values (-19.1±2.8% vs -22.1±1.8%).
Why the study?
Does arterial hypertension affect the early detection of cardiotoxicity by 2D Speckle Tracking Imaging in patients with triple negative breast cancer undergoing anthracycline-containing chemotherapy?
Cohort (n=70)
Does arterial hypertension affect the early detection of cardiotoxicity by 2D Speckle Tracking Imaging in patients with triple negative breast cancer undergoing anthracycline-containing chemotherapy?
Anthracycline-containing chemotherapy leads to an early reduction in global longitudinal strain, which can be detected by 2D Speckle Tracking Imaging at 8 weeks.
Hypertension links to lower baseline GLS in TNBC; leaves open whether it alters early cardiotoxicity detection by speckle tracking.
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Avalyan et al. (2017) conducted a cohort in Triple negative breast cancer (n=70). Arterial hypertension vs. Normal blood pressure was evaluated on Global longitudinal strain (GLS). Arterial hypertension in women with triple negative breast cancer was associated with lower baseline global longitudinal strain compared to normal values (-19.1±2.8% vs -22.1±1.8%).
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